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See Latest ArticlesGenetic deficiencies of innate immune signalling in human infectious disease : The Lancet Infectious Diseases
The Lancet Infectious Diseases, 10/27/09
Vosse EVD et al. – Knowledge of innate immune signalling has allowed the identification of defects in such patients. However, some patients have enhanced susceptibility to pathogens even though no mutations have been found in the candidate genes identified thus far. Whereas a few patients might have autoantibodies against type–1 cytokines, others might harbour mutations in new genes and pathways that still need to be identified.
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