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See Latest ArticlesProgress towards a dengue vaccine
The Lancet Infectious Diseases, 10/27/09
Webster DP et al. – Vaccine development has been slowed by fears that immunisation might predispose individuals to the severe form of dengue infection. A pipeline of candidate vaccines now exists, including live attenuated, inactivated, chimeric, DNA, and viral–vector vaccines, some of which are at the stage of clinical testing. In this Review, the authors present what is understood about dengue pathogenesis and its implications for vaccine design, the progress that is being made in the development of a vaccine, and the future challenges.
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