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See Latest ArticlesRegulation of phenylacetic acid degradation genes of Burkholderia cenocepacia K56-2
BMC Microbiology, 10/21/09
Hamlin JNR et al. – The PA catabolic genes of B. cenocepacia K56–2 are induced by PA and other related compounds, are negatively regulated by PaaR (named herein), a TetR–type regulator, and are subjected to catabolic repression by glucose and succinate. As the PA catabolic pathway of B. cenocepacia appears to be induced during growth in synthetic cystic fibrosis medium, further research is necessary to determine the relevance of this pathway in CF–like conditions and in other host–pathogen interactions.
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