Infectious Dis. Medical News about Chagas' Disease

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Pharmacological Inhibition of Transforming Growth Factor [beta] Signaling Decreases Infection and Prevents Heart Damage in Acute Chagas' Disease
Antimicrobial Agents and Chemotherapy, 11/05/09

Waghabi MC et al. – Inhibition of TGF–[beta] signaling in vivo appears to potently decrease T. cruzi infection and to prevent heart damage in a preclinical mouse model. This suggests that this class of molecules may represent a new therapeutic agent for acute and chronic Chagas' disease that warrants further clinical exploration.

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Neurological Manifestations in Chagas Disease without Cardiac Dysfunction: Correlation between Dysfunction of the Parasympathetic Nervous System and White Matter Lesions in the Brain
Journal of Neuroimaging, 10/13/09 Relevance Score: 67%

Shifting priorities in vector biology to improve control of vector-borne disease
Tropical Medicine & International Health, 10/08/09 Relevance Score: 67%

NT-proCNP And CNP Do Not Correlate In Patients With Chagas Disease: Role For Neutral Endopeptidase
Journal of Cardiovascular Pharmacology, 11/11/09 Relevance Score: 66%

Chagas Disease. Independent Risk Factor for Stroke
Stroke, 11/02/09 Relevance Score: 64%

Chagas Disease. Independent Risk Factor for Stroke
Stroke, 10/19/09 Relevance Score: 64%