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EstA protein, a novel virulence factor of Streptococcus pneumoniae, induces nitric oxide and pro-inflammatory cytokine production in RAW 264.7 macrophages through NF-kB/MAPK
Microbial Pathogenesis, 11/06/09
Kang EH et al. - The data suggests that EstA protein is a novel inducer of NO and pro-inflammatory cytokines by activating the NFkB, p38 and ERK 1/2 MAPK pathways during inflammatory responses.
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