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See Latest ArticlesMucosal immunology of the genital and gastrointestinal tracts and HIV-1 infection
Journal of Reproductive Immunology, 10/19/09
Mestecky J et al. – Evaluation of HIV–specific antibodies in sera and external secretions, including vaginal washes and semen, unexpectedly revealed a selective lack of IgA responses. Moreover, specific antibody–secreting cells in peripheral blood were of the IgG isotype, even in mucosally infected individuals. Whether humoral responses to previously or newly encountered antigens are compromised in HIV–1–infected persons is under current investigation.
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