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See Latest ArticlesMutational Analysis Reveals a Noncontractile but Interactive Role of Actin and Profilin in Viral RNA-Dependent RNA Synthesis
Journal of Virology, 10/13/09
Harpen M et al. – The results suggest that actin acts as a classical transcription factor for the virus by divalent–cation–dependent binding to the viral template and that profilin acts as a transcriptional cofactor, in part by associating with actin. This essential viral role of actin is independent of its contractile cellular role.
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