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See Latest ArticlesE1 Mutants Identify a Critical Region in the Trimer Interface of the Semliki Forest Virus Fusion Protein
Journal of Virology, 10/13/09
Liu CY et al. – The D188A mutant was infectious, although trimerization and fusion required a lower pH. While there are extensive contacts between E1 subunits in the homotrimer, the D188K mutant identifies an important "hot spot" for protein–protein interactions within the core trimer.
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