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Virion-Associated Vpr of Human Immunodeficiency Virus Type 1 Triggers Activation of Apoptotic Events and Enhances Fas-Induced Apoptosis in Human T Cells
Journal of Virology, 10/12/09
Arokium H et al. – The findings suggest that virion–associated Vpr can contribute to the depletion of CD4+ lymphocytes either directly or by enhancing Fas–mediated apoptosis during acute HIV–1 infection and in AIDS.
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