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Very Late-Onset Group B Streptococcus Meningitis, Sepsis, and Systemic Shigellosis due to Interleukin-1 Receptor–Associated Kinase-4 Deficiency
Clinical Infectious Diseases, 10/14/09
Krause JC et al. – Peripheral blood cells obtained from the patient and her brother did not respond to stimulation with either interleukin-1beta or lipopolysaccharide. Sequencing of the interleukin-1 receptor–associated kinase-4 gene revealed 2 novel mutations.
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