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Inhibition of erythrocyte invasion and Plasmodium falciparum Merozoite Surface Protein 1 processing by human IgG1 and IgG3 antibodies
Infection and Immunity, 10/20/09
Lazarou M et al. – The chimeric human Abs will enable investigators to examine the role of human Fc(gamma)–receptors in immunity to malaria using a transgenic parasite and mouse model, and may prove useful in humans for neutralizing parasites as an adjunct to anti–malarial drug therapy.
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