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See Latest ArticlesLocalization of the lipopolysaccharide recognition complex in the human healthy and inflamed premature and adult gut
Inflammatory Bowel Disease, 09/29/09
Buurman WA et al. – The absence of MD–2 in the immature neonatal gut suggests impaired LPS sensing, which could predispose neonates to NEC upon microbial colonization of the immature intestine. The apparent expression of MD–2 by Paneth cells supports the critical concept that these cells respond to luminal bacterial products in order to maintain homeostasis with the intestinal microbiota in vivo.
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