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Usefulness and limitations of QuantiFERON-TB Gold in Japanese rheumatoid arthritis patients: proposal to decrease the lower cutoff level for assessing latent tuberculosis infection
Modern Rheumatology, 10/19/09
Maeda T et al. – QFT–G is a useful diagnostic method due to its superior specificity, but the use of a cutoff value of 0.35 IU/ml will likely result in an underestimate. The authors propose that a lower interferon–gamma (IFN–gamma) titer of 0.1 IU/ml be adopted when deciding to administer anti–TB drugs before initiation of TNF inhibitors.
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