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Schmidt H et al. – Whereas antibiotic therapy has improved the treatment of most infectious diseases, the mortality of bacterial meningitis has not significantly changed since the introduction of penicillin and the availability of intensive care units. The prerequisites for good outcome are prompt diagnosis and rapid initiation of antibacterial treatment. In industrialized countries, immunosuppressive treatment with dexamethasone initiated prior to antibiotic treatment has become part of the guidelines in order to alleviate the pro–inflammatory storm induced by the disease.


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