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Heterologous prime-boost strategy in non-human primates combining the infective dengue virus and a recombinant protein in a formulation suitable for human use
International Journal of Infectious Diseases, 10/01/09
Valdes I et al. – The results obtained in the present work support the approach of heterologous prime–boosting, in either order prime or boost, combining the chimeric protein PD5 (formulated in alum–CPS–A) and an infective dengue virus. The latter could potentially be replaced by an attenuated vaccine candidate.
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