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See Latest ArticlesNovel Antimalarial Aminoquinolines: Heme Binding and Effects on Normal or Plasmodium falciparum-Parasitized Human Erythrocytes
Antimicrobial Agents and Chemotherapy, 09/23/09
Omodeo–Sale F et al. – The results suggest that the antimalarial activity of AM1 or AP4b is likely due to inhibition of hemozoin formation and that the efficacy of these compounds against the CQ–resistant strains can be ascribed to their hydrophobicity and capacity to accumulate in the vacuolar lipid.
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