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Your Article Summary
Multifaceted Evasion of the Interferon Response by Cytomegalovirus
Journal of Interferon & Cytokine Research, 10/07/09
Marshall EE et al. – The HCMV immediate early gene 1 protein (pUL123) interacts with Stat2 and inhibits transcriptional activation of IFN–regulated genes. Infection also causes reduction in the abundance of p48/IRF9, a component of the ISGF3 transcription factor complex.
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