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See Latest ArticlesInfluenza Viruses Control the Vertebrate Type I Interferon System: Factors, Mechanisms, and Consequences
Journal of Interferon & Cytokine Research, 10/01/09
Wolff T et al. – This article highlights the recent progress in the understanding of key interactions of influenza viruses with the type I IFN defense, which are central to viral virulence. A main focus is on corruptions of IFN–dependent antiviral functions mediated by the cellular receptors RIG–I and PKR and their blockade by the viral NS1 protein.
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