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The use of mushroom-forming fungi for the production of N-glycosylated therapeutic proteins
Trends in Microbiology, 09/17/09
Berends E et al. – The market for N–glycosylated therapeutic proteins represents multi–billion dollars in sales and is growing more than 10% each year. This requires cost–effective production platforms that display correct and homogeneous N–glycosylation. Based on recent results, the authors propose to use mushroom–forming basidiomycetes for the production of N–glycosylated therapeutic proteins.
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