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A pre-S gene chip to detect pre-S deletions in hepatitis B virus large surface antigen as a predictive marker for hepatoma risk in chronic hepatitis B virus carriers
BMC: Journal of Biomedical Science, 09/16/09
Shen FC et al. – The pre–S1/2 mutants may emerge during the long–term persistence of the HBV genome in carriers and facilitate HCC development. Combined detection of pre–S mutations, other markers of HBV replication, and viral titers, offers a reliable predictive method for HCC risks in chronic HBV carriers.
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