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Kinetics of interferon-gamma producing cytomegalovirus (CMV)-specific CD4+ and CD8+ T lymphocytes and the risk of subsequent CMV viremia after allogeneic hematopoietic stem cell transplantation
Transplant Infectious Disease, 09/17/09
Eid AJ et al. – Higher levels of CMV–specific CD4+ and CD8+ T lymphocytes were associated with subsequent CMV viremia after HSCT. The association between CMV viremia and the degree of decline in CMV–specific T lymphocytes suggests that severe disruption in homeostatic CMV–specific immune environment contributes to the immunopathogenesis of CMV after allogeneic HSCT.
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