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Caught in action: mechanistic insights into antibody-mediated inhibition of Plasmodium merozoite invasion
Trends in Parasitology, 09/14/09
Treeck M et al. – Apical membrane antigen 1 plays an essential role in host cell invasion by apicomplexan parasites. A recent study by Collins et al. investigated the mode of action of an anti–AMA1 invasion–inhibitory antibody. They demonstrated the interference of this antibody with invasion complex formation, which was dependent in turn on a single conserved tyrosine residue in AMA1.
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Accuracy of Serological Testing for the Diagnosis of Prevalent Neurocysticercosis in Outpatients with Epilepsy, Eastern Cape Province, South Africa
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