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See Latest ArticlesSgrA, a Nidogen-binding LPXTG Surface Adhesin Implicated in Biofilm Formation, and EcbA, a Collagen Binding MSCRAMM of Hospital Acquired Enterococcus faecium
Infection and Immunity, 09/29/09
Hendrickx APA et al. – The acm and scm genes, encoding two other E. faecium MSCRAMMs were expressed at the mRNA level together with sgrA during all phases of growth, whereas ecbA was only expressed in exponential and late exponential phase, suggesting orchestered expression of these adhesins. Expression of these surface proteins that bind to extracellular matrix proteins and involved in biofilm formation (SgrA) may contribute to the pathogenesis of hospital acquired E. faecium infections.
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