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See Latest ArticlesLarge cell change of hepatocytes in chronic viral hepatitis represents a senescent-related lesion
Human Pathology, 09/16/09
Ikeda H et al. – The frequent expression of senescent features and the absence of proliferative or apoptotic activity suggest that large cell change represents senescence. The parallel increase in large cell change and hepatocellular carcinoma in chronic hepatitis B raises the possibility that cellular senescence develops as a safeguard against malignant transformation rather than as a precursor of hepatocellular carcinoma.
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Today in Hepatitis...keeping you current
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