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See Latest ArticlesTreatment of visceral leishmaniasis with intravenous pentamidine and oral fluconazole in an HIV-positive patient with chronic renal failure — a case report and brief review of the literature
International Journal of Infectious Diseases, 09/17/09
Rybniker J et al. – The authors report the case of an HIV–positive patient with visceral leishmaniasis and several relapses after treatment with the two first–line anti–leishmanial drugs, liposomal amphotericin B and miltefosine. End–stage renal failure occurred in 2007 when the patient was on long–term treatment with miltefosine. A relapse of leishmaniasis in 2008 was successfully treated with a novel combination regimen of intravenous pentamidine and oral fluconazole. Secondary prophylaxis with fluconazole monotherapy did not prevent parasitological relapse of leishmaniasis.
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