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Immune effector mechanisms against schistosomiasis: looking for a chink in the parasites armour
Trends in Parasitology, 09/22/09
Wilson RA et al. – A successful vaccine will likely require a cocktail of antigens rather than a single recombinant protein. In addition, ways need to be found of keeping the immune system on permanent alert, either to achieve adequate inhibition of protein function in adults, or because a trickle of incoming parasites does not amplify the secondary response.
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