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Interleukin-21 induces the differentiation of human umbilical cord blood CD34-lineage- cells into pseudomature lytic NK cells
BMC Immunology, 08/31/09
Bonanno G et al. – This study underpins a novel role for IL–21 in the differentiation of pseudo–mature lytic NK cells in a synergistic context with IL–15, and identifies a potential strategy to expand functional NK cells for immunotherapy.
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