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Defining molecular phenotypes of human papillomavirus–associated oropharyngeal squamous cell carcinoma: Validation of three-class hypothesis
Otolaryngology Head and Neck Surgery, 08/28/09
Weinberger PM et al. – Tumors classified by HPV DNA presence and p16 expression have different molecular phenotypes. This is the first demonstration of overexpression of beta–catenin in HPV–active OSCC. HPV–active OSCC may share a similar ontogeny to HPV–caused cervical cancer.
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