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Transmission-Dependent Tolerance to Multiclonal Plasmodium falciparum Infection
The Journal of Infectious Diseases, 08/25/09
Färnert A et al. – In a comparative assessment in a high-transmission area in Tanzania, multiclonal infections conferred a reduced risk. The different nonlinear associations between the number of clones and malaria morbidity suggest that levels of tolerance to multiclonal infections are transmission dependent as a result of cumulative exposure to antigenically diverse P. falciparum infections.
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