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See Latest ArticlesStevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Consequence of Treatment of an Emerging Pathogen
Pediatric Emergency Care, 09/02/09
Mistry RD et al. – The authors report a case of Stevens–Johnson syndrome/toxic epidermal necrolysis secondary to trimethoprim–sulfamethoxazole therapy for presumed community–associated methicillin–resistant Staphylococcus aureus infection. Although the association between SJS/TEN and the sulfonamide class of antibiotics is well established, the increasing prevalence of CA–MRSA has left practitioners with limited regimens to effectively treat skin and soft tissue infections in the outpatient setting. In the case of SSTIs, alternative treatment of these infections should be considered, especially when the bacterial pathogen is unknown.
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