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Bacterial susceptibility to topical antimicrobials and clinical outcome in bacterial keratitis
Investigative Ophthalmology and Visual Science, 08/19/09
Kaye SB et al. – For fluoroquinolone monotherapy there was significant association between the MIC of the antimicrobial prescribed and clinical outcome for all bacteria except CNS and Streptococcus spp. The approach used in this study, if employed prospectively, could allow topical breakpoint susceptibility concentrations to be determined for individual antimicrobial and bacterial combinations.
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