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Dart JKG et al. – The scleritis associated with AK is rarely associated with extracorneal invasion and usually responds to systemic anti–inflammatory treatment combined with topical biguanides. Therapeutic keratoplasty retains a role for therapy of some severe complications of AK but not for initial treatment. With modern management, 90% of patients can expect to retain visual acuity of 6/12 or better and fewer than 2% become blind, although treatment may take 6 months or more.

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