Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. Use of Antiemetic Agents in Acute Gastroenteritis 3. 2008 Exclusive Survey—Earnings: Good news for primary care income 4. Medicare pay-for-reporting effort draws fire from frustrated doctors 5. Debunking Myths in the US Healthcare System
Your Article Summary
See Latest ArticlesPreoperative antifungal therapy may improve survival in patients with Aspergillus brain abscess
Clinical Neurology and Neurosurgery, 07/29/09
Wasay M et al. – Cerebral aspergillosis is largely a disease of immunocompetent pts (80%), with a overall mortality of 40%. The outcome was significantly better in pts treated with antifungal therapy (especially itraconazole) before surgery, suggesting a possible beneficial effect of pre-surgical treatment with antifungal therapy.
Methods- Study of whether preoperative antifungal therapy positively influences clinical outcome in pts with Aspergillus brain abscess
- Assessment of 25 pts with confirmed diagnosis of cerebral aspergillosis
- Comparison of baseline characteristics and outcomes of pts treated with either amphotericin B or itraconazole either preoperatively (11 pts) or postoperatively (14 pts)
- Comparable baseline clinical characteristics between the 2 treatment groups: age, gender, coma at presentation, immunosuppression, number of abscesses, and interval between presentation and surgery
- Overall outcome significantly better for pts treated with antifungal therapy preoperatively
- All 11 pts who received antifungal therapy preoperatively survived
- Only preoperative itraconazole treatment statistically associated with improved survival vs delayed treatment
Related Articles
Atypical presentation of chronic granulomatous disease in an adolescent boy with frontal lobe located Aspergillus abscess mimicking intracranial tumor
Child's Nervous System, 10/29/09
Relevance Score: 66%
Central nervous system Aspergillus infection after epidural analgesia: diagnosis, therapeutic challenges, and literature review
Diagnostic Microbiology and Infectious Disease, 10/22/09
Relevance Score: 66%
Innate Immunity to Aspergillus Species
Clinical Microbiology Reviews, 10/16/09
Relevance Score: 66%
2-Hydroxydiplopterol, a new cytotoxic pentacyclic triterpenoid from the halotolerant fungus Aspergillus variecolor B-17
Archives of Pharmacal Research, 10/14/09
Relevance Score: 66%
Spectrum of fungal keratitis in central China
Clinical and Experimental Ophthalmology, 11/03/09
Relevance Score: 65%
Today in CNS Infectious Disease...keeping you current
Receive free subspecialty "5-minute updates" via email
Tick-borne encephalitis in children: an update on epidemiology and diagnosis
Expert Review of Anti-infective Therapy, 12/18/09
Reactivation and centripetal spread of herpes simplex virus complicating acoustic neuroma resection
Surgical Neurology, 12/18/09
The regulatory role of the MisR/S two-component system in hemoglobin utilization in Neisseria meningitidis
Infection and Immunity, 12/18/09
Article Search
Sponsor