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A variant in the gene FUT9 is associated with susceptibility to placental malaria infection
Human Molecular Genetics, 07/28/09
Sikora M et al. – Haplotypic analysis revealed a similarly strong association of a common haplotype of four SNPs including rs3811070. FUT9 codes for a fucosyl–transferase that is catalyzing the last step in the biosynthesis of the Lewis–x antigen, which forms part of the Lewis blood group–related antigens. These results therefore suggest an involvement of this antigen in the pathogenesis of placental malaria infection.
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