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Kostov K et al. - Tuberculous spondylitis (TS) frequently poses both diagnostic and therapeutic challenges. Repetitive lateral plain radiographs, MRI and QuantiFERON TB Gold test have proven of highest diagnostic value at this stage of the disease. The presence of clinical data, accelerated ESR levels, plain radiography and MRI evidence of an inflammatory process preceding the occurrence of bone destruction and the formation of paravertebral soft tissue collection provide sufficient reasons to conduct QuantiFERON TB Gold or T SPOT.TB testing and start an anti tuberculous therapy.

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