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Antiviral therapy in compensated and decompensated cirrhotic patients with chronic HCV infection
Expert Opinion in Pharmacotherapy, 07/01/09
Iacobellis A et al. - Treatment is only recommended for a well-compensated liver cirrhosis, whereas antiviral therapy is commonly not implemented in cirrhotics with signs of liver decompensation, over the concern that the use of peginterferon and ribavirin might expose patients to severe treatment-related side effects. This review focuses on data available to support both efficacy and safety of antiviral therapy in both compensated and decompensated cirrhotic patients.
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Today in Hepatitis...keeping you current
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Different models of HBeAg seroconversion predicated by on-treatment ALT and HBV DNA profiles
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Plasma HCV-RNA decline in the first 48 h identifies hepatitis C virus mono-infected but not HCV/HIV-coinfected patients with an undetectable HCV viral load at week 4 of peginterferon-alfa-2a/ribavirin therapy
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