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See Latest ArticlesThe membrane expression of Neisseria meningitidis adhesin A (NadA) increases the proimmune effects of MenB OMVs on human macrophages, compared with NadA– OMVs, without further stimulating their proinflammatory activity on circulating monocytes
Journal of Leukocyte Biology, 07/07/09
Tavano R et al. - The activity of NadA-positive E. coli OMVs was similar to that of control OMVs. NadA in MenB OMVs acted at adhesin concentrations 106 times lower than those required to stimulate cells with free NadA delta 351–405.
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