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Identification of bisindolylmaleimides and indolocarbazoles as inhibitors of HCV replication by tube-capture-RT-PCR
Antiviral Research , 07/02/09

Murakami Y et al. - In addition to the known inhibitors of HCV replication included in the library, the assay identified the PKC inhibitor bisindolylmaleimide I as an HCV replication inhibitor. BIM I was also effective in reducing the viral protein level in genotype 1b and 2a subgenomic replicon cells, indicating inhibition of HCV replication.

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Emergence of hepatitis C virus genotype 4: phylogenetic analysis reveals three distinct epidemiological profiles
Journal of Clinical Microbiology, 10/02/09 Relevance Score: 93%

CD81 expression in peripheral blood lymphocytes before and after treatment with interferon and ribavirin in HIV/HCV coinfected patients
HIV Medicine, 10/01/09 Relevance Score: 93%

Declining hepatitis C virus (HCV) prevalence in pregnant women: impact of anti-HCV screening of donated blood
Transfusion, 11/23/09 Relevance Score: 91%

Serum concentrations of interleukin 1î², cxcl10, and interferon-î³ in mixed cryoglobulinemia associated with hepatitis c infection
Journal of Rheumatology, 11/20/09 Relevance Score: 91%

Health-related quality of life in dialysis patients with HCV infection
The International Journal of Artificial Organs, 10/30/09 Relevance Score: 91%