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Safety and Pharmacokinetics of Chimeric Anti-Shiga Toxin 1 and Anti-Shiga Toxin 2 Monoclonal Antibodies in Healthy Volunteers
Antimicrobial Agents and Chemotherapy, 07/01/09
Bitzan M et al. - The conclusion is that c(alpha)Stx1 and c(alpha)Stx2, given as individual or combined short intravenous infusions, are well tolerated. These results form the basis for future safety and efficacy trials with patients with STEC infections to ameliorate or prevent HUS and other complications.
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