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Two vs. three sputum samples for microscopic detection of tuberculosis in a high HIV prevalence population
The International Journal of Tuberculosis and Lung Disease, 06/29/09
Noeske J et al. - In this population with a high prevalence of human immunodeficiency virus (HIV) with late case presentation, smear microscopy of two morning specimens detected at least as many positive cases as the classical strategy, and no cases were lost before treatment. Two specimens for initial TB suspect screening can thus be recommended, also without excessive workload. Comparative studies in populations presenting with paucibacillary sputum are needed to determine the equivalent quality and yield of an alternative strategy with two spot specimens at consultation.
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