Infectious Dis. Medical News about fluconazole

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Reduced fluconazole susceptibility of Candida albicans isolates in women with recurrent vulvovaginal candidiasis: effects of long-term fluconazole therapy
Diagnostic Microbiology and Infectious Disease, 06/17/09

Shahid Z et al. - Fluconazole resistance and resultant failure to control Candida vaginitis (vulvovaginal candidiasis) remains extremely uncommon; however, long-term clinically relevant decrease in fluconazole susceptibility undoubtedly occurs and accompanies prolonged fluconazole chemoprophylaxis. Accordingly, in patients with refractory vaginitis or breakthrough infections due to Candida albicans, in vitro susceptibility testing is essential to optimally manage vaginitis.

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Economic evaluation of posaconazole vs fluconazole in the prevention of invasive fungal infections in patients with GVHD following haematopoietic SCT
Bone Marrow Transplantation, 10/07/09 Relevance Score: 88%

Fungicidal effect of photodynamic therapy against fluconazole-resistant Candida albicans and Candida glabrata
Mycoses, 11/05/09 Relevance Score: 84%

Prophylaxis with itraconazole is more effective than prophylaxis with fluconazole in neutropenic patients with hematological malignancies: a meta-analysis of randomized-controlled trials
Medical Oncology, 11/04/09 Relevance Score: 84%

Enhancement of Secretory Aspartyl Protease production in biofilms of Candida albicans exposed to sub-inhibitory concentrations of fluconazole
Mycoses, 10/30/09 Relevance Score: 84%

Candida albicans prosthetic hip infection in elderly patients: Is fluconazole monotherapy an option
Scandinavian Journal of Infectious Diseases, 10/14/09 Relevance Score: 84%