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See Latest ArticlesReduced ability of hemagglutinin of the CAM-70 measles virus vaccine strain to use receptors CD46 and SLAM
Vaccine , 06/12/09
Kato S et al. - In peripheral blood lymphocytes and monocyte-derived dendritic cells, the CAM-70 strain did not grow efficiently. Infection with recombinant MVs revealed that impaired growth of the CAM-70 strain was attributed to the H gene only partly in PBL and largely in Mo-DC. Thus, impaired fusion-inducing ability of the H protein may be one of the underlying molecular mechanisms resulting in the attenuation of the CAM-70 strain.
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