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Functional characteristics of HIV-1 subtype C compatible with increased heterosexual transmissibility
AIDS, 06/01/09
Walter BL et al. - As CD4+-CCR5+-T cells are key targets for genital HIV infection and cervical selection can favor compact V1-V2 loops and 316T, which increase viral infectivity, the authors propose that these conserved subtype-C motifs may contribute to transmission and spread of this subtype.
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