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Tattevin P et al. - Since 2001, a dramatic increase in methicillin-resistant Staphylococcus aureus (MRSA) infections has been observed in the United States, mostly related to emergence of the USA300 clone in the community and subsequently in hospitals. Residents of long-term care facilities (LTCFs) are at risk for colonization with antimicrobial drug–resistant bacteria, including MRSA. After they have been colonized, these residents are at increased risk for infections. Although it is assumed that transfer of patients between acute-care hospitals and LTCFs provides an ongoing cycle for the introduction of MRSA between these facilities, few studies have described the molecular epidemiology of MRSA in LTCFs. The authors report the prevalence and distribution of MRSA genotypes among clinical isolates obtained over a 10-year period (1997–2006) at the main LTCF in San Francisco, California, USA.


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