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Safety and Availability of Dapivirine (TMC120) Delivered from an Intravaginal Ring
AIDS Research and Human Retroviruses, 05/01/09
Romano J et al. - Vaginal delivery of 200mg or 25mg dapivirine from intravaginal rings (IVRs) was evaluated over a 7-day period in two phase 1 safety trials (IPM001 and IPM008, respectively) in a total of 25 healthy women 19 to 46 years of age. The IVR was generally safe and well tolerated with similar adverse events observed in the placebo and dapivirine groups.
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