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See Latest ArticlesTopographic Features Retained after Antibiotic Modification of Ti Alloy Surfaces: Retention of Topography with Attachment of Antibiotics
Clinical Orthopedics and Related Research, 04/21/09
Ketonis C et al. - Antibiotic-coupled samples representing all three geometries were uniformly covered with antibiotic, resisted colonization by Staphylococcus aureus for longer than 8 hours, and retained their biocompatibility as assessed by normal attachment and morphology of preosteocytic MLO-A5 cells. Using this technique, the authors believe it is possible to passivate many complex implant designs/geometries as a first step toward covalent bonding of antibiotics or other bioactive factors.
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