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Bosentan Enhances Viral Load via Endothelin-1 Receptor Type-A–Mediated p38 Mitogen-Activated Protein Kinase Activation While Improving Cardiac Function During Coxsackievirus-Induced Myocarditis
Circulation Research, 02/17/09
Marchant D et al. - Bosentan, a prescribed vasodilator, improves cardiac function but enhances viral load and myocarditis severity through ETRA mediated p38 MAPK activation; p38 MAPK is a desirable antiviral target. Caution must be exercised during treatment of suspected infectious myocarditis with supportive vasoactive remedies.
Today in Antimicrobials...keeping you current
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Combination antibiotic therapy with macrolides improves survival in intubated patients with community-acquired pneumonia
Intensive Care Medicine, 12/09/09
Screening of some Tanzanian medicinal plants for their trypanocidal and cytotoxic activities
Phytotherapy Research, 12/09/09
Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial
The Lancet - Early Online Publication, 12/08/09
Today in Cardiovascular...keeping you current
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Anti-perforin neutralizing antibody reduces myocardial injury in viral myocarditis
Cardiology in the Young, 12/08/09
Routine Performance of Endomyocardial Biopsy Decreases the Incidence of Orthotopic Heart Transplant for Myocarditis
The Journal of Heart and Lung Transplantation, 12/04/09
Identifying Cardiovascular Syphilis at Operation
The American Journal of Cardiology, 12/04/09
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