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See Latest ArticlesAutophagy, an immunologic magic bullet: Mycobacterium tuberculosis phagosome maturation block and how to bypass it
Future Microbiology, 09/30/08
Deretic V - Mycobacterium tuberculosis is a facultative intracellular pathogen that parasitizes host macrophages where it persists in immature phagosomes by avoiding their maturation into phagolysosomes. In a search of a cellular mechanism that can bypass the tubercule bacillus-imposed PI3P block, researchers have uncovered a new general bactericidal process, autophagy, which can eliminate intracellular pathogens. This is a new, rapidly growing field replete with possibilities for novel, previously untried immunologic and pharmacologic interventions applicable not only to TB but to other stubborn bacterial, parasitic and viral diseases.
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Rapid viral diagnosis for acute febrile respiratory illness in children in the Emergency Department
Cochrane Reviews, 10/26/09
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American Family Physician, 11/02/09
Usefulness of pneumococcal antigen detection in pleural effusion for the rapid diagnosis of infection by Streptococcus pneumoniae
European Journal of Pediatrics, 10/12/09
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