Mechanisms of avoidance of host immunity by Neisseria meningitidis and its effect on vaccine development
Lo H et al. - Neisseria meningitidis remains an important cause of severe sepsis and meningitis worldwide. To date, available vaccines only protect individuals against subsets of meningococcal strains. However, two promising vaccines are currently being assessed in clinical trials and appear to offer good prospects for an effective means of protecting individuals against endemic serogroup B disease, which has proven to be a major challenge in vaccine research. [more...]
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