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See Latest ArticlesCathepsin B release after imatinib-mediated lysosomal membrane permeabilization triggers BCR–ABL cleavage and elimination of chronic myelogenous leukemia cells
Leukemia, 11/24/09
Puissant A et al. – The authors describe an original pathway by which Imatinib participates to the elimination of CML cells through LMP and CB–mediated specific degradation of BCR–ABL.
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Today in Basic Science/Genetics...keeping you current
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Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancer
Oncogene, 03/22/10
Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression
Oncogene, 03/22/10
ETV6/RUNX1 abrogates mitotic checkpoint function and targets its key player MAD2L1
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Today in Leukemia/Lymphoma...keeping you current
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Clofarabine-induced Capillary Leak Syndrome in a Child With Refractory Acute Lymphoblastic Leukemia
Journal of Pediatric Hematology/Oncology, 03/22/10
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